The Prevention Technology Transfer Center Network developed The Six Elements of Effective Coalitions Resource Toolkit (Resource Toolkit) as part of its overall mission to strengthen prevention practitioners’ capacities to organize, facilitate, and sustain effective prevention coalitions and collaborations that prevent substance misuse and its related consequences. This Resource Toolkit includes various resources related to six key elements, or coalition characteristics, shown through research to promote the adoption of science-based prevention practices that generate improved community conditions and behavioral health outcomes for youth. The Resource Toolkit is a companion piece to The Six Elements of Effective Coalitions Research Overview, which introduces and defines each of the Six Elements of Effective Coalitions downloadable PDF.