This guide will introduce the concept of “Restorative Prevention,” a mental framework for rethinking our approach to community-based substance misuse prevention efforts. The goal of this framework is to build healthy communities through a process of systemic equity that restores communities to a state better than they once were. I will define terms and key concepts as a proposed foundation for adopting restorative and equity-centered practices, particularly among those demographics that existing health and prevention systems are failing to serve or support.